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HIV Protease Cleavage of Procaspase 8 is Necessary for Death of HIV-Infected Cells

Numerous host and viral factors are capable of causing death of HIV infected cells, uninfected bystander cells, or both. We assessed the relevance of HIV protease in infected cell killing by mutating its obligate substrate for death, procaspase 8. VSV pseudotyped HIV infection of cells expressing WT...

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Detalhes bibliográficos
Main Authors: Nie, Zilin, Bren, Gary D, Rizza, Stacey A, Badley, Andrew D
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548307/
https://ncbi.nlm.nih.gov/pubmed/18818774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874357900802010001
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