Analysis of HIV Protease Killing Through Caspase 8 Reveals a Novel Interaction Between Caspase 8 and Mitochondria

Human Immunodeficiency Virus (HIV) protease initiates apoptosis of HIV-infected cells by proteolytic cleavage of procaspase 8, creating a novel peptide termed casp8p41. Expression of casp8p41 alone is sufficient to initiate caspase-dependent cell death associated with mitochondrial depolarization. S...

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Main Authors: Algeciras-Schimnich, Alicia, Belzacq-Casagrande, Anne-Sophie, Bren, Gary D, Nie, Zilin, Taylor, Julie A, Rizza, Stacey A, Brenner, Catherine, Badley, Andrew D
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548302/
https://ncbi.nlm.nih.gov/pubmed/18818773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874357900701010039
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