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Sphingosine kinase 1/S1P receptor signaling axis controls glial proliferation in mice with Sandhoff disease

Sphingosine-1-phosphate (S1P) is a lipid-signaling molecule produced by sphingosine kinase in response to a wide number of stimuli. By acting through a family of widely expressed G protein-coupled receptors, S1P regulates diverse physiological processes. Here we examined the role of S1P signaling in...

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Detalhes bibliográficos
Main Authors: Wu, Yun-Ping, Mizugishi, Kiyomi, Bektas, Meryem, Sandhoff, Roger, Proia, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548282/
https://ncbi.nlm.nih.gov/pubmed/18424450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn126
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