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Deletion of macrophage-inflammatory protein 1α retards neurodegeneration in Sandhoff disease mice
Sandhoff disease is a prototypical lysosomal storage disorder in which a heritable deficiency of a lysosomal enzyme, β-hexosaminidase, results in the storage of the enzyme's substrates in lysosomes. As with many of the other lysosomal storage diseases, neurodegeneration is a prominent feature....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC420410/ https://ncbi.nlm.nih.gov/pubmed/15155903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400625101 |
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