Regulation of Chk2 Ubiquitination and Signaling through Autophosphorylation of Serine 379

The Chk2 protein kinase protects genome integrity by promoting cell cycle arrest or apoptosis in response to DNA double-strand breaks, and Chk2 mutations are found in both familial and sporadic cancers. Exposure of cells to ionizing radiation (IR) or radiomimetic drugs induces Chk2 phosphorylation b...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Lovly, Christine M., Yan, Ling, Ryan, Christine E., Takada, Saeko, Piwnica-Worms, Helen
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
主題:
Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547006/
https://ncbi.nlm.nih.gov/pubmed/18644861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00821-08
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍