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On the relationship between folding and chemical landscapes in enzyme catalysis

Elucidating the relationship between the folding landscape of enzymes and their catalytic power has been one of the challenges of modern enzymology. The present work explores this issue by using a simplified folding model to generate the free-energy landscape of an enzyme and then to evaluate the ac...

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書誌詳細
主要な著者: Roca, Maite, Messer, Benjamin, Hilvert, Donald, Warshel, Arieh
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544547/
https://ncbi.nlm.nih.gov/pubmed/18779576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803405105
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