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On the relationship between folding and chemical landscapes in enzyme catalysis
Elucidating the relationship between the folding landscape of enzymes and their catalytic power has been one of the challenges of modern enzymology. The present work explores this issue by using a simplified folding model to generate the free-energy landscape of an enzyme and then to evaluate the ac...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2544547/ https://ncbi.nlm.nih.gov/pubmed/18779576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803405105 |
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