Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase

Myeloid cells, including neutrophils and macrophages, play important roles in innate immune defense against acute bacterial infections. Myeloid Src family kinases (SFKs) p59/61(hck) (Hck), p58(c-fgr) (Fgr), and p53/56(lyn) (Lyn) are known to control integrin β(2) signal transduction and FcγR-mediate...

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Autores principales: Paul, Robert, Obermaier, Bianca, Van Ziffle, Jessica, Angele, Barbara, Pfister, Hans-Walter, Lowell, Clifford A., Koedel, Uwe
Formato: Artigo
Lenguaje:Inglês
Publicado: The Society for Leukocyte Biology 2008
Materias:
Receptors, Signal Transduction, and Genes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538596/
https://ncbi.nlm.nih.gov/pubmed/18625913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0208118
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