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Apoptosis Is Essential for Neutrophil Functional Shutdown and Determines Tissue Damage in Experimental Pneumococcal Meningitis

During acute bacterial infections such as meningitis, neutrophils enter the tissue where they combat the infection before they undergo apoptosis and are taken up by macrophages. Neutrophils show pro-inflammatory activity and may contribute to tissue damage. In pneumococcal meningitis, neuronal damag...

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Main Authors: Koedel, Uwe, Frankenberg, Tobias, Kirschnek, Susanne, Obermaier, Bianca, Häcker, Hans, Paul, Robert, Häcker, Georg
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682662/
https://ncbi.nlm.nih.gov/pubmed/19478887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000461
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