Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase

Myeloid cells, including neutrophils and macrophages, play important roles in innate immune defense against acute bacterial infections. Myeloid Src family kinases (SFKs) p59/61(hck) (Hck), p58(c-fgr) (Fgr), and p53/56(lyn) (Lyn) are known to control integrin β(2) signal transduction and FcγR-mediate...

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Detalhes bibliográficos
Main Authors: Paul, Robert, Obermaier, Bianca, Van Ziffle, Jessica, Angele, Barbara, Pfister, Hans-Walter, Lowell, Clifford A., Koedel, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2008
Assuntos:
Receptors, Signal Transduction, and Genes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538596/
https://ncbi.nlm.nih.gov/pubmed/18625913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0208118
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