Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase

Myeloid cells, including neutrophils and macrophages, play important roles in innate immune defense against acute bacterial infections. Myeloid Src family kinases (SFKs) p59/61(hck) (Hck), p58(c-fgr) (Fgr), and p53/56(lyn) (Lyn) are known to control integrin β(2) signal transduction and FcγR-mediate...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Paul, Robert, Obermaier, Bianca, Van Ziffle, Jessica, Angele, Barbara, Pfister, Hans-Walter, Lowell, Clifford A., Koedel, Uwe
Format: Artigo
Langue:Inglês
Publié: The Society for Leukocyte Biology 2008
Sujets:
Receptors, Signal Transduction, and Genes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538596/
https://ncbi.nlm.nih.gov/pubmed/18625913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0208118
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