Correlation between Pyrazinamide Activity and pncA Mutations in Mycobacterium tuberculosis Isolates in Taiwan

A total of 76 clinical Mycobacterium tuberculosis isolates from Taiwan were tested for pyrazinamidase activity, pyrazinamide susceptibility, and pncA mutations. Frequency of resistance to PZA rose with increases in resistance to first-line drugs. Of 17 pyrazinamide-resistant strains, 7 (3 of which h...

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Detaylı Bibliyografya
Yayımlandı:	Antimicrob Agents Chemother
Asıl Yazarlar:	Huang, Tsi-Shu, Lee, Susan Shin-Jung, Tu, Hui-Zin, Huang, Wen-Kuei, Chen, Yao-Shen, Huang, Chung-Kai, Wann, Shue-Ren, Lin, Hsi-Hsun, Liu, Yung-Ching
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 2003
Konular:	Mechanisms of Resistance
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.11.3672-3673.2003
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Correlation between Pyrazinamide Activity and pncA Mutations in Mycobacterium tuberculosis Isolates in Taiwan

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