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Correlation between Pyrazinamide Activity and pncA Mutations in Mycobacterium tuberculosis Isolates in Taiwan

A total of 76 clinical Mycobacterium tuberculosis isolates from Taiwan were tested for pyrazinamidase activity, pyrazinamide susceptibility, and pncA mutations. Frequency of resistance to PZA rose with increases in resistance to first-line drugs. Of 17 pyrazinamide-resistant strains, 7 (3 of which h...

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Bibliografske podrobnosti
Main Authors: Huang, Tsi-Shu, Lee, Susan Shin-Jung, Tu, Hui-Zin, Huang, Wen-Kuei, Chen, Yao-Shen, Huang, Chung-Kai, Wann, Shue-Ren, Lin, Hsi-Hsun, Liu, Yung-Ching
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC253789/
https://ncbi.nlm.nih.gov/pubmed/14576145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3672-3673.2003
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