pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis Isolates from Northwestern Russia

Thirty-six pyrazinamide-resistant and eight pyrazinamide-susceptible Mycobacterium tuberculosis isolates from Russia were analyzed for their pncA mutations. Thirty-one (86.1%) of the resistant isolates had a mutation either in pncA or upstream of the gene. Twenty of the 23 different mutations found...

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Autors principals: Marttila, Harri J., Marjamäki, Merja, Vyshnevskaya, Elena, Vyshnevskiy, Boris I., Otten, Tatjana F., Vasilyef, Alexandr V., Viljanen, Matti K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC89360/
https://ncbi.nlm.nih.gov/pubmed/10390239
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