pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis Isolates from Northwestern Russia

Thirty-six pyrazinamide-resistant and eight pyrazinamide-susceptible Mycobacterium tuberculosis isolates from Russia were analyzed for their pncA mutations. Thirty-one (86.1%) of the resistant isolates had a mutation either in pncA or upstream of the gene. Twenty of the 23 different mutations found...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Marttila, Harri J., Marjamäki, Merja, Vyshnevskaya, Elena, Vyshnevskiy, Boris I., Otten, Tatjana F., Vasilyef, Alexandr V., Viljanen, Matti K.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89360/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10390239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.7.1764
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