Correlation between Pyrazinamide Activity and pncA Mutations in Mycobacterium tuberculosis Isolates in Taiwan

A total of 76 clinical Mycobacterium tuberculosis isolates from Taiwan were tested for pyrazinamidase activity, pyrazinamide susceptibility, and pncA mutations. Frequency of resistance to PZA rose with increases in resistance to first-line drugs. Of 17 pyrazinamide-resistant strains, 7 (3 of which h...

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Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Huang, Tsi-Shu, Lee, Susan Shin-Jung, Tu, Hui-Zin, Huang, Wen-Kuei, Chen, Yao-Shen, Huang, Chung-Kai, Wann, Shue-Ren, Lin, Hsi-Hsun, Liu, Yung-Ching
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 2003
Onderwerpen:	Mechanisms of Resistance
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.11.3672-3673.2003
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