Correlation between Pyrazinamide Activity and pncA Mutations in Mycobacterium tuberculosis Isolates in Taiwan

A total of 76 clinical Mycobacterium tuberculosis isolates from Taiwan were tested for pyrazinamidase activity, pyrazinamide susceptibility, and pncA mutations. Frequency of resistance to PZA rose with increases in resistance to first-line drugs. Of 17 pyrazinamide-resistant strains, 7 (3 of which h...

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Bibliografiske detaljer
Main Authors: Huang, Tsi-Shu, Lee, Susan Shin-Jung, Tu, Hui-Zin, Huang, Wen-Kuei, Chen, Yao-Shen, Huang, Chung-Kai, Wann, Shue-Ren, Lin, Hsi-Hsun, Liu, Yung-Ching
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC253789/
https://ncbi.nlm.nih.gov/pubmed/14576145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3672-3673.2003
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