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The Endogenous and Cell Cycle-dependent Phosphorylation of tau Protein in Living Cells: Implications for Alzheimer’s Disease

In Alzheimer’s disease the neuronal microtubule-associated protein tau becomes highly phosphorylated, loses its binding properties, and aggregates into paired helical filaments. There is increasing evidence that the events leading to this hyperphosphorylation are related to mitotic mechanisms. Hence...

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Библиографические подробности
Главные авторы: Illenberger, Susanne, Zheng-Fischhöfer, Qingyi, Preuss, Ute, Stamer, Karsten, Baumann, Karlheinz, Trinczek, Bernhard, Biernat, Jacek, Godemann, Robert, Mandelkow, Eva-Maria, Mandelkow, Eckhard
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 1998
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC25374/
https://ncbi.nlm.nih.gov/pubmed/9614189
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