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The Endogenous and Cell Cycle-dependent Phosphorylation of tau Protein in Living Cells: Implications for Alzheimer’s Disease

In Alzheimer’s disease the neuronal microtubule-associated protein tau becomes highly phosphorylated, loses its binding properties, and aggregates into paired helical filaments. There is increasing evidence that the events leading to this hyperphosphorylation are related to mitotic mechanisms. Hence...

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書誌詳細
主要な著者: Illenberger, Susanne, Zheng-Fischhöfer, Qingyi, Preuss, Ute, Stamer, Karsten, Baumann, Karlheinz, Trinczek, Bernhard, Biernat, Jacek, Godemann, Robert, Mandelkow, Eva-Maria, Mandelkow, Eckhard
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC25374/
https://ncbi.nlm.nih.gov/pubmed/9614189
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