The Endogenous and Cell Cycle-dependent Phosphorylation of tau Protein in Living Cells: Implications for Alzheimer’s Disease

In Alzheimer’s disease the neuronal microtubule-associated protein tau becomes highly phosphorylated, loses its binding properties, and aggregates into paired helical filaments. There is increasing evidence that the events leading to this hyperphosphorylation are related to mitotic mechanisms. Hence...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Illenberger, Susanne, Zheng-Fischhöfer, Qingyi, Preuss, Ute, Stamer, Karsten, Baumann, Karlheinz, Trinczek, Bernhard, Biernat, Jacek, Godemann, Robert, Mandelkow, Eva-Maria, Mandelkow, Eckhard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 1998
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25374/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9614189/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.6.1495
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