Female ROMK null mice manifest more severe Bartter II phenotype on renal function and higher PGE(2) production

ROMK null mice with a high survival rate and varying severity of hydronephrosis provide a good model to study type II Bartter syndrome pathophysiology (26). During the development of such a colony, we found that more male than female null mice survived, 58.7% vs. 33.3%. To investigate the possible m...

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Bibliographic Details
Main Authors: Yan, Qingshang, Yang, Xinbo, Cantone, Alessandra, Giebisch, Gerhard, Hebert, Steven, Wang, Tong
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
Subjects:
Water and Electrolyte Homeostasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536865/
https://ncbi.nlm.nih.gov/pubmed/18579648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00051.2007
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