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Targeted Single Wall Carbon Nanotube Mediated Pt(IV) Prodrug Delivery Using Folate as a Homing Device
Most low molecular weight platinum anticancer drugs have short blood circulation times that are reflected in their reduced tumor uptake and intracellular DNA binding. A platinum(IV) complex of the formula c,c,t-[Pt(NH(3))(2)Cl(2)(O(2)CCH(2)CH(2)CO(2)H)(O(2)CCH(2)CH(2)CONH-PEG-FA)] (1) containing a f...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536766/ https://ncbi.nlm.nih.gov/pubmed/18661990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja803036e |
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