Soluble Single-Walled Carbon Nanotubes as Longboat Delivery Systems for Platinum(IV) Anticancer Drug Design

Amine functionalized soluble single walled carbon nanotubes (SWNTs) were derivatized with cisplatin prodrug conjugates as a delivery system by which to internalize multiple prodrug centers. The platinum(IV) complex, c,c,t-[Pt(NH(3))(2)Cl(2)(OEt)(O(2)CCH(2)CH(2)CO(2)H)], was tethered to the surface o...

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Bibliographische Detailangaben
Hauptverfasser: Feazell, Rodney P., Nakayama-Ratchford, Nozomi, Dai, Hongjie, Lippard, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2505197/
https://ncbi.nlm.nih.gov/pubmed/17569542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja073231f
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