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Encapsulation of Pt(iv) prodrugs within a Pt(ii) cage for drug delivery

This report presents a novel strategy that facilitates delivery of multiple, specific payloads of Pt(iv) prodrugs using a well-defined supramolecular system. This delivery system comprises a hexanuclear Pt(ii) cage that can host four Pt(iv) prodrug guest molecules. Relying on host–guest interactions...

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Bibliografische gegevens
Gepubliceerd in:Chem Sci
Hoofdauteurs: Zheng, Yao-Rong, Suntharalingam, Kogularamanan, Johnstone, Timothy C., Lippard, Stephen J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303084/
https://ncbi.nlm.nih.gov/pubmed/25621144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc01892c
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