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Mechanistic Studies of the Anticancer Activity of An Octahedral Hexanuclear Pt(II) Cage

The cellular response evoked by a hexanuclear platinum complex, Pt(6)L(4) (1), is reported. Compound 1, a 3-nm octahedral cage formed by self-assembly of six Pt(II) centers and four 2,4,6-tris(4-pyridyl)-1,3,5-triazine ligands (L), exhibits promising in vitro potency against a panel of human cancer...

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Detalhes bibliográficos
Publicado no:Inorganica Chim Acta
Main Authors: Zheng, Yao-Rong, Suntharalingam, Kogularamanan, Bruno, Peter M., Lin, Wei, Wang, Weixue, Hemann, Michael T., Lippard, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094802/
https://ncbi.nlm.nih.gov/pubmed/27818526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ica.2016.03.021
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