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Eliminating phosphorylation sites of the parathyroid hormone receptor type 1 differentially affects stimulation of phospholipase C and receptor internalization

The parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor (PTH1R) belongs to family B of seven-transmembrane-spanning receptors and is activated by PTH and PTHrP. Upon PTH stimulation, the rat PTH1R becomes phosphorylated at seven serine residues. Elimination of all PTH1R phosphorylation si...

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Detalhes bibliográficos
Main Authors: Miedlich, Susanne U., Abou-Samra, Abdul B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536737/
https://ncbi.nlm.nih.gov/pubmed/18577695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00036.2008
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