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Parathyroid hormone induces bone formation in phosphorylation-deficient PTHR1 knockin mice

Activation of G protein-coupled receptors by agonists leads to receptor phosphorylation, internalization of ligand receptor complexes, and desensitization of hormonal response. The role of parathyroid hormone (PTH) receptor 1, PTHR1, is well characterized and known to regulate cellular responsivenes...

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Detalhes bibliográficos
Main Authors: Datta, Nabanita S., Samra, Tareq A., Abou-Samra, Abdul B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361988/
https://ncbi.nlm.nih.gov/pubmed/22338074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00380.2011
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