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Parathyroid hormone induces bone formation in phosphorylation-deficient PTHR1 knockin mice

Activation of G protein-coupled receptors by agonists leads to receptor phosphorylation, internalization of ligand receptor complexes, and desensitization of hormonal response. The role of parathyroid hormone (PTH) receptor 1, PTHR1, is well characterized and known to regulate cellular responsivenes...

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Bibliographic Details
Main Authors: Datta, Nabanita S., Samra, Tareq A., Abou-Samra, Abdul B.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361988/
https://ncbi.nlm.nih.gov/pubmed/22338074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00380.2011
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