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Role of PTH1R internalization in osteoblasts and bone mass using a phosphorylation-deficient knock-in mouse model

Phosphorylation, internalization, and desensitization of G protein-coupled receptors, such as the parathyroid hormone (PTH) and PTH-related peptide (PTHrP) receptor (PTH1R), are well characterized and known to regulate the cellular responsiveness in vitro. However, the role of PTH1R receptor phospho...

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Detalhes bibliográficos
Main Authors: Datta, Nabanita S, Samra, Tareq A, Mahalingam, Chandrika D, Datta, Tanuka, Abou-Samra, Abdul B
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771320/
https://ncbi.nlm.nih.gov/pubmed/20929987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0227
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