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Negative Regulation of Parathyroid Hormone (PTH)-Activated Phospholipase C by PTH/PTH-Related Peptide Receptor Phosphorylation and Protein Kinase A

PTH binding to the PTH/PTHrP receptor activates adenylate cyclase/protein kinase A (PKA) and phospholipase C (PLC) pathways and increases receptor phosphorylation. The mechanisms regulating PTH activation of PLC signaling are poorly understood. In the current study, we explored the role of PTH/PTHrP...

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Detalhes bibliográficos
Main Authors: Tawfeek, Hesham A. W., Abou-Samra, Abdul B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488210/
https://ncbi.nlm.nih.gov/pubmed/18450967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1375
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