Contributions of Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Signaling Pathways to the Anabolic Effect of PTH on Bone

PTH regulates osteoblastic function by activating PTH/PTHrP receptors (PTH1Rs), which trigger several signaling pathways in parallel, including cAMP/protein kinase A (PKA) and, via both phospholipase-C (PLC)-dependent and PLC-independent mechanisms, protein kinase C (PKC). These signaling functions...

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Main Authors: Yang, D, Singh, R, Divieti, P, Guo, J, Bouxsein, ML, Bringhurst, F R
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976286/
https://ncbi.nlm.nih.gov/pubmed/17376756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2007.02.001
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