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Pentalenolactone Biosynthesis. Molecular Cloning and Assignment of Biochemical Function to PtlI, a Cytochrome P450 of Streptomyces avermitilis

[Image: see text] A gene cluster encoding all of the enzymes for the biosynthesis of the antibiotic pentalenolactone (1) has recently been identified inStreptomyces avermitilis. The biosynthetic gene cluster contains theptlI (SAV2999) gene which encodes a cytochrome P450 (CYP183A1). PtlI was cloned...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Quaderer, Richard, Omura, Satoshi, Ikeda, Haruo, Cane, David E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533730/
https://ncbi.nlm.nih.gov/pubmed/17017767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0639214
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