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Crystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis

The non-heme iron dioxygenase PtlH from the soil organism Streptomyces avermitilis is a member of the iron(II)/α-ketoglutarate–dependent dioxygenase superfamily and catalyzes an essential reaction in the biosynthesis of the sesquiterpenoid antibiotic pentalenolactone. To investigate the structural b...

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Autori principali: You, Zheng, Omura, Satoshi, Ikeda, Haruo, Cane, David E., Jogl, Gerwald
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010413/
https://ncbi.nlm.nih.gov/pubmed/17942405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M706358200
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