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The medial-Golgi Ion Pump Pmr1 Supplies the Yeast Secretory Pathway with Ca(2+) and Mn(2+) Required for Glycosylation, Sorting, and Endoplasmic Reticulum-Associated Protein Degradation

The yeast Ca(2+) adenosine triphosphatase Pmr1, located in medial-Golgi, has been implicated in intracellular transport of Ca(2+) and Mn(2+) ions. We show here that addition of Mn(2+) greatly alleviates defects of pmr1 mutants in N-linked and O-linked protein glycosylation. In contrast, accurate sor...

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Hlavní autoři: Dürr, Gabriele, Strayle, Jochen, Plemper, Richard, Elbs, Saskia, Klee, Saskia K., Catty, Patrice, Wolf, Dieter H., Rudolph, Hans K.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC25337/
https://ncbi.nlm.nih.gov/pubmed/9571246
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