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The medial-Golgi Ion Pump Pmr1 Supplies the Yeast Secretory Pathway with Ca(2+) and Mn(2+) Required for Glycosylation, Sorting, and Endoplasmic Reticulum-Associated Protein Degradation
The yeast Ca(2+) adenosine triphosphatase Pmr1, located in medial-Golgi, has been implicated in intracellular transport of Ca(2+) and Mn(2+) ions. We show here that addition of Mn(2+) greatly alleviates defects of pmr1 mutants in N-linked and O-linked protein glycosylation. In contrast, accurate sor...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC25337/ https://ncbi.nlm.nih.gov/pubmed/9571246 |
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