Cab45 is required for Ca(2+)-dependent secretory cargo sorting at the trans-Golgi network

Ca(2+) import into the lumen of the trans-Golgi network (TGN) by the secretory pathway calcium ATPase1 (SPCA1) is required for the sorting of secretory cargo. How is Ca(2+) retained in the lumen of the Golgi, and what is its role in cargo sorting? We show here that a soluble, lumenal Golgi resident...

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Bibliographic Details
Main Authors: von Blume, Julia, Alleaume, Anne-Marie, Kienzle, Christine, Carreras-Sureda, Amado, Valverde, Miguel, Malhotra, Vivek
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2012
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529532/
https://ncbi.nlm.nih.gov/pubmed/23266954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207180
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