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Pmr1, a Golgi Ca(2+)/Mn(2+)-ATPase, is a regulator of the target of rapamycin (TOR) signaling pathway in yeast
The rapamycin·FKBP12 complex inhibits target of rapamycin (TOR) kinase in TORC1. We screened the yeast nonessential gene deletion collection to identify mutants that conferred rapamycin resistance, and we identified PMR1, encoding the Golgi Ca(2+)/Mn(2+)-ATPase. Deleting PMR1 in two genetic backgrou...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1693834/ https://ncbi.nlm.nih.gov/pubmed/17095607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604303103 |
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