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The Aspergillus fumigatus P-Type Golgi Apparatus Ca(2+)/Mn(2+) ATPase PmrA Is Involved in Cation Homeostasis and Cell Wall Integrity but Is Not Essential for Pathogenesis

The Aspergillus fumigatus ΔpmrA (Golgi apparatus Ca(2+)/Mn(2+) P-type ATPase) strain has osmotically suppressible basal growth defects and cationic tolerance associated with increased expression of calcineurin pathway genes. Despite increased β-glucan and chitin content, it is hypersensitive to cell...

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Detalhes bibliográficos
Main Authors: Pinchai, Nadthanan, Juvvadi, Praveen Rao, Fortwendel, Jarrod R., Perfect, B. Zachary, Rogg, Luise E., Asfaw, Yohannes G., Steinbach, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837981/
https://ncbi.nlm.nih.gov/pubmed/20097742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00378-09
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