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Regulatable Ras Activity Is Critical for Proper Establishment and Maintenance of Polarity in Aspergillus fumigatus

Here we show that expression of a constitutively activated RasA allele, as the sole source of Ras activity, revealed novel Ras-induced phenotypes, including excessive vacuolar expansion and spontaneous lysis of hyphal compartments. These findings highlight the requirement for balanced Ras activity i...

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Detalhes bibliográficos
Main Authors: Fortwendel, Jarrod R., Juvvadi, Praveen R., Rogg, Luise E., Steinbach, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127644/
https://ncbi.nlm.nih.gov/pubmed/21278230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00315-10
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