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Plasma Membrane Localization Is Required for RasA-Mediated Polarized Morphogenesis and Virulence of Aspergillus fumigatus

Ras is a highly conserved GTPase protein that is essential for proper polarized morphogenesis of filamentous fungi. Localization of Ras proteins to the plasma membrane and endomembranes through posttranslational addition of farnesyl and palmitoyl residues is an important mechanism through which cell...

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Autors principals: Fortwendel, Jarrod R., Juvvadi, Praveen R., Rogg, Luise E., Asfaw, Yohannes G., Burns, Kimberlie A., Randell, Scott H., Steinbach, William J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416062/
https://ncbi.nlm.nih.gov/pubmed/22562470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00091-12
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