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Plasma Membrane Localization Is Required for RasA-Mediated Polarized Morphogenesis and Virulence of Aspergillus fumigatus

Ras is a highly conserved GTPase protein that is essential for proper polarized morphogenesis of filamentous fungi. Localization of Ras proteins to the plasma membrane and endomembranes through posttranslational addition of farnesyl and palmitoyl residues is an important mechanism through which cell...

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Detalhes bibliográficos
Main Authors: Fortwendel, Jarrod R., Juvvadi, Praveen R., Rogg, Luise E., Asfaw, Yohannes G., Burns, Kimberlie A., Randell, Scott H., Steinbach, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416062/
https://ncbi.nlm.nih.gov/pubmed/22562470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00091-12
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