Transcriptional Regulation of Chitin Synthases by Calcineurin Controls Paradoxical Growth of Aspergillus fumigatus in Response to Caspofungin

Attenuated activity of echinocandin antifungals at high concentrations, known as the “paradoxical effect,” is a well-established phenomenon in Candida albicans and Aspergillus fumigatus. In the yeast C. albicans, upregulation of chitin biosynthesis via the protein kinase C (PKC), high-osmolarity gly...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fortwendel, Jarrod R., Juvvadi, Praveen R., Perfect, B. Zachary, Rogg, Luise E., Perfect, John R., Steinbach, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849361/
https://ncbi.nlm.nih.gov/pubmed/20124000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00854-09
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados