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Transcriptional Regulation of Chitin Synthases by Calcineurin Controls Paradoxical Growth of Aspergillus fumigatus in Response to Caspofungin

Attenuated activity of echinocandin antifungals at high concentrations, known as the “paradoxical effect,” is a well-established phenomenon in Candida albicans and Aspergillus fumigatus. In the yeast C. albicans, upregulation of chitin biosynthesis via the protein kinase C (PKC), high-osmolarity gly...

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Detaylı Bibliyografya
Asıl Yazarlar: Fortwendel, Jarrod R., Juvvadi, Praveen R., Perfect, B. Zachary, Rogg, Luise E., Perfect, John R., Steinbach, William J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849361/
https://ncbi.nlm.nih.gov/pubmed/20124000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00854-09
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