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A helix scaffold for the assembly of active protein kinases

Structures of set of serine-threonine and tyrosine kinases were investigated by the recently developed bioinformatics tool Local Spatial Patterns (LSP) alignment. We report a set of conserved motifs comprised mostly of hydrophobic residues. These residues are scattered throughout the protein sequenc...

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Autors principals: Kornev, Alexandr P., Taylor, Susan S., Ten Eyck, Lynn F.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533684/
https://ncbi.nlm.nih.gov/pubmed/18787129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807988105
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