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Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism
The surface comparison of different serine–threonine and tyrosine kinases reveals a set of 30 residues whose spatial positions are highly conserved. The comparison between active and inactive conformations identified the residues whose positions are the most sensitive to activation. Based on these r...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1693824/ https://ncbi.nlm.nih.gov/pubmed/17095602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607656103 |
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