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Comparative surface geometry of the protein kinase family

Identifying conserved pockets on the surfaces of a family of proteins can provide insight into conserved geometric features and sites of protein–protein interaction. Here we describe mapping and comparison of the surfaces of aligned crystallographic structures, using the protein kinase family as a m...

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Détails bibliographiques
Auteurs principaux: Thompson, Elaine E, Kornev, Alexandr P, Kannan, Natarajan, Kim, Choel, Ten Eyck, Lynn F, Taylor, Susan S
Format: Artigo
Langue:Inglês
Publié: Wiley Subscription Services, Inc., A Wiley Company 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786965/
https://ncbi.nlm.nih.gov/pubmed/19610074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.209
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