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A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains
Cyclic nucleotides (cAMP and cGMP) regulate multiple intracellular processes and are thus of a great general interest for molecular and structural biologists. To study the allosteric mechanism of different cyclic nucleotide binding (CNB) domains, we compared cAMP-bound and cAMP-free structures (PKA,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275311/ https://ncbi.nlm.nih.gov/pubmed/18404204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000056 |
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