Chronic Administration of Tenofovir to Rhesus Macaques from Infancy through Adulthood and Pregnancy: Summary of Pharmacokinetics and Biological and Virological Effects

The reverse transcriptase (RT) inhibitor tenofovir (TFV) is highly effective in the simian immunodeficiency virus (SIV) macaque model of human immunodeficiency virus infection. The current report describes extended safety and efficacy data on 32 animals that received prolonged (≥1- to 13-year) daily...

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Sonraí Bibleagrafaíochta
Main Authors: Van Rompay, Koen K. A., Durand-Gasselin, Lucie, Brignolo, Laurie L., Ray, Adrian S., Abel, Kristina, Cihlar, Tomas, Spinner, Abigail, Jerome, Christopher, Moore, Joseph, Kearney, Brian P., Marthas, Marta L., Reiser, Hans, Bischofberger, Norbert
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2008
Ábhair:
Antiviral Agents
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533487/
https://ncbi.nlm.nih.gov/pubmed/18573931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00350-08
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