Chronic Administration of Tenofovir to Rhesus Macaques from Infancy through Adulthood and Pregnancy: Summary of Pharmacokinetics and Biological and Virological Effects

The reverse transcriptase (RT) inhibitor tenofovir (TFV) is highly effective in the simian immunodeficiency virus (SIV) macaque model of human immunodeficiency virus infection. The current report describes extended safety and efficacy data on 32 animals that received prolonged (≥1- to 13-year) daily...

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Detaylı Bibliyografya
Asıl Yazarlar: Van Rompay, Koen K. A., Durand-Gasselin, Lucie, Brignolo, Laurie L., Ray, Adrian S., Abel, Kristina, Cihlar, Tomas, Spinner, Abigail, Jerome, Christopher, Moore, Joseph, Kearney, Brian P., Marthas, Marta L., Reiser, Hans, Bischofberger, Norbert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533487/
https://ncbi.nlm.nih.gov/pubmed/18573931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00350-08
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