Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor

Hepatic overproduction of apolipoprotein B (apoB)-containing lipoproteins is characteristic of the dyslipidemia associated with insulin resistance. Recently, we demonstrated that the flavonoid naringenin, like insulin, decreased apoB secretion from HepG2 cells by activation of both the phosphoinosit...

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Hlavní autoři: Allister, Emma M., Mulvihill, Erin E., Barrett, P. Hugh R., Edwards, Jane Y., Carter, Lindsey P., Huff, Murray W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533411/
https://ncbi.nlm.nih.gov/pubmed/18587069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800297-JLR200
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