טוען...
Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants
Regulation of homologous recombination (HR) represents the best-characterized DNA repair function of p53. The role of p53 phosphorylation in DNA repair is largely unknown. Here, we show that wild-type p53 repressed repair of DNA double-strand breaks (DSBs) by HR in a manner partially requiring the A...
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| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2532731/ https://ncbi.nlm.nih.gov/pubmed/18697815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn503 |
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