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Purification, crystallization and preliminary X-ray analysis of human mannose-binding lectin-associated serine protease-1 (MASP-1) catalytic region

MASP-1, a multidomain serine protease, is a component of the lectin pathway of complement. Its precise function is unknown, although it seems to enhance the complement-activating capacity of MASP-2, a related enzyme. MASP-1 has also been implicated as playing a role in blood coagulation. It is mostl...

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Détails bibliographiques
Auteurs principaux: Dobó, József, Harmat, Veronika, Sebestyén, Edina, Beinrohr, László, Závodszky, Péter, Gál, Péter
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531277/
https://ncbi.nlm.nih.gov/pubmed/18765903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910802294X
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