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SUMO-modified Sp3 represses transcription by provoking local heterochromatic gene silencing
Modification of many transcription factors including Sp3 and steroidogenic factor 1 with the small ubiquitin-like modifier (SUMO) is associated with transcriptional repression. Here, we show that SUMOylation of transcription factors bound to DNA provokes the establishment of compacted repressive chr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529347/ https://ncbi.nlm.nih.gov/pubmed/18617891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.127 |
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